SatSight Dx Faster MSI triage.

SatSight Dx flags microsatellite-stable colorectal cancer cases from the H&E slide that already exists. An ensemble of 100 AI models, validated on 1,000+ slides across five independent external cohorts.

Try the live demo Request integration

Research use only

H&E whole-slide image of a colorectal resection
SATSIGHT DX · INFERENCE CONFIDENCE-AWARE CALL
Problem & solution

Most CRC cases are MSS. We test all of them anyway.

Every colorectal case needs an MSI result, and today that means molecular sequencing: three weeks and about €500 per case.

Today With SatSight Dx
Turnaround per case ~3 weeks ~1 hour
Cost per case ~€500 Under €10
New material needed Sequencing, reagents, lab time None
What gets analysed Tumor DNA The H&E slide
What comes back Binary result Score + 95% CI

Evaluated on 1,000+ slides from five independent external cohorts · ROC-AUC 0.965 · Sensitivity 98% · Specificity 78.1% · Every slide returns MSS, MSI or Undetermined

Try it · Live demo

Try it on a slide. See the prediction.

An example anonymised H&E case. Illustrative demo, all data shown is for illustrative purposes only. Drag the divider, switch between attention heatmap and tissue segmentation, and inspect details with the lens.

SatSight Dx · Interactive demo
Original H&E slide Attention heatmap overlay
Original Attention map
Attention
LowNeutralHigh
Classes
Tumor Normal Mucus Stroma Debris Lymphocytes

For research use only

AI Analysis #SS-2419
Attention · MSI score 0.97
MSS0.50MSI
Recommendation
Reflex MMR / MSI-PCR confirmation

MSI-High signature detected at 0.97 model confidence. Recommend reflex MMR-IHC or MSI-PCR before initiating immune-checkpoint therapy and flag for Lynch-syndrome workup.

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ROC-AUC
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Sensitivity
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Specificity
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Inference
How it works

One slide in. A confidence-aware call.

Drop the H&E

No new hardware, no extra staining.

Drag-and-drop a whole-slide image, or run SatSight Dx natively inside Roche Digital Pathology or Morphle Lab environments.

100-model ensemble

Every slide, scored 100 times.

The mean MSI probability and 95% confidence interval surface MSS, Undetermined and MSI cases.

Pathologist-ready report

Classification, heatmap, segmentation.

Every report includes the call, attention heatmap and tissue segmentation across tumor, stroma, mucus, lymphocytes and normal epithelium.

0% ROC-AUC 0.965 · five external cohorts
0% Sensitivity · 1,000+ slides
0% Specificity · 1,000+ slides
Who it's for

One model. Four operating modes.

Choose the one that fits how your team already works.

Pathology labs

Reflex MSI from H&E.

  • Whatever scanner you use: connect to the API and SatSight Dx runs
  • Native in Roche Digital Pathology · Morphle Lab
Pharma & trials

Stratify for immunotherapy.

  • Retrospective biomarker analysis on archive cohorts
  • Validated across diverse staining protocols and populations
Diagnostics & IVD

Benchmark your assay.

  • Uncertainty-aware AI baseline trained on routine H&E
  • ROC-AUC 0.965 across five external cohorts
Research & AMCs

Find spatial patterns.

  • Attention heatmaps paired with morphology
  • Segmentation: tumor · stroma · mucus · lymphocytes · epithelium

All modes: research use only

Get SatSight Dx

Bring your WSI. We'll bring the model and the result.

Speak with the PAICON team about deploying SatSight Dx in your workflow environment: via API, Roche Digital Pathology or Morphle Lab.